A significant part of the anime series focuses on teens and young adults who have a strong connection between them, apart from having an intriguing storyline and fabulous animation. If the anime duos are likable, anime fans will cherish this friendship and hold on to the same series for decades. We all must have been hooked on that one anime series, and the reason why we are watching the show is because of that one iconic duo and the creators are messing with our feelings and not bringing them back together! Such a disappointment, isn’t it
50. Best Anime Duos of All Time: Denji & Power
- Anime: Chainsaw Man
- IMDb Rating: 8.3/10
- Streaming Platform: HiAnime, Crunchyroll, Prime Video, Netflix
Denji and Power are a crazy pair, pure entertainment! This friendship is established on shared idiocy, food fights, and all that unbreakable trust. While one is a wild devil with zero shame, the other is a goof with nothing more in his life goals than a chainsaw. They are one of the funniest duos for their constant bickering, ridiculous antics, and reckless behavior
However, beneath all this chaos lies the brotherhood, they’d kill each other without a second question. The bond is not all about comedies but finding that one person who genuinely knows you and doesn’t matter how weird you are. They are not mature, but pure gold as their bond. If you’re ready to experience love from a crazy, funny, and very emotional couple Chainsaw Man is a must-watch.
49. Anya & Becky
- Anime: Spy x Family
- IMDb Rating: 8.3/10
- Streaming Platform: HiAnime, Crunchyroll, Netflix, Jio Cinema, Prime Video
Anya and Becky is a pure comedy gold duo, one is a mind-reading gremlin and the other is a rich, dramatic bestie. One is a pint-sized telepath who cannot even get her secret life together, and the other is a confident, rich girl who is into romance and elegance. Their hilarious misunderstandings, over-the-top fantasies, and Becky’s over-the-top reactions to Anya’s antics are so hilarious!
But it’s not all fun, there’s a lovely friendship in the middle. They were the first who truly formed a bond in the anime. Becky and Anya adore having a real friend. Whether they come up with any scheme, fantasize, or create chaos at school, it is the sweetest couple without which no fan will ever have boredom. It’s the kind of couple one wants to look out for those hilarious moments alongside sweet friendship gestures; they’re just the kind of duo for it!
48. Tanjiro & Nezuko
- Anime: Demon Slayer: Kimetsu no Yaiba
- IMDb Rating: 8.7/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll, Jio Cinema
The sibling bond is the strongest blade to have ever cut, and that’s what forms the heart of their journey. One is a gentle warrior yet fierce, while the other is a demon who will not give up her humanity. Their love for each other makes every battle emotional—Tanjiro fights to the death to protect Nezuko, and she unleashes her monstrous strength to save him. But it’s not all tears and intensity!
The cute interactions between them, especially Nezuko’s playful little moves and Tanjiro’s overprotection towards her, can be quite light-hearted and funny moments. The relationship is the perfect blend of warmth, comedy, and raw emotions, proving family is well worth any struggle.
47. Best Anime Duos of All Time: Loid & Yor
- Anime: Spy x Family
- IMDb Rating: 8.3/10
- Streaming Platform: HiAnime, Crunchyroll, Netflix, Jio Cinema, Prime Video
Spy and assassin, posing as the perfect married couple—what could possibly go wrong? He is the epitome of professionalism, always collected and composed; she is sweet and deadly but clueless about normal life. Just comedy gold as Loid tries to keep everything in order, and Yor just goes along with things. There exists a reality amidst all this joke and intriguing reality that binds the two together concerning something as gaudy, hollow, and artificial, as a pretend family into which they just entered, even if unknowing. They hide something irreplaceable, though probably the least knowing how.
46. Subaru & Rem
- Anime: Re: Zero – Starting Life in Another World
- IMDb Rating: 8.1/10
- Streaming Platform: HiAnime, Crunchyroll, Prime Video
Subaru and Rem in Re: Zero is one of those love stories that will break your heart and heal it at the same time. Bad-boy hero: one part reckless, stubborn mess-and she’s all dedicated, good-natured warrior. But just put together the most emotional couples with just plain moments of utter heartbreak and deep support for one another.
Their chemistry does not go too much with love; it’s more of a thing of how Rem believes in Subaru when nobody else does, and little by little how much she holds to Subaru’s heart. You can’t help but fall for these two. No matter whether through tragic confessions, heart-wrenching sacrifices, or tiny endearing small moments of banter.
45. Ichigo & Rukia
- Anime: Bleach: Thousand-Year Blood War
- IMDb Rating: 9.0/10
- Streaming Platform: HiAnime, Disney+ Hotstar, Crunchyroll, Netflix
A legendary partnership results when a hotheaded substitute Soul Reaper meets a sharp-tongued warrior. Built on mutual respect, witty banter, and an unbreakable bond that pushes both to grow, Ichigo the reckless fighter always ready to throw himself into danger, but Ruika is that one who keeps him grounded by just a sarcastic remark or a well-placed punch.
But beneath all the jokes, there’s this deep connection, this one which goes deeper than words. They challenge each other, protect each other, and even define many ways each other’s paths define. Whether they’re fighting side by side or just sharing some quiet time, their chemistry is electric. If you love duos with an intense connection, unforgettable humor, and pure emotional weight, watch Bleach: Thousand-Year Blood War
44. Best Anime Duos of All Time: Gojo Satoru & Suguru Geto
- Anime: Jujutsu Kaisen
- IMDb Rating: 8.5/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll
Once inseparable, now tragic opposites, Gojo Satoru and Suguru Geto represent the elegance and tragedy of true friendship. From Jujutsu Kaisen, the relationship began with taunting, naive pride, and a promise of changing the world together. A cocky, untouchable Gojo-the strongest sorcerer-and his perfect counterbalance, the strategic-genius Geto.
But once their ideals clashed, it was a lighthearted dispute that turned into a devastating betrayal. Their interactions are both hilarious and gut-wrenching, making every moment between them carry immense weight. Even when they stand on opposite sides, there’s an undeniable connection that lingers. If you love stories of friendship, loss, and what-ifs, their journey will captivate you and break your heart all at once.
43. Vanitas & Noé
- Anime: The Case Study of Vanitas
- IMDb Rating: 7.6/10
- Streaming Platform: HiAnime, Crunchyroll
A clash of personalities that works well somehow, The Case Study of Vanitas presents an odd but intriguingly perfect pair with the chaotic eccentric doctor who purportedly saves vampires and the impulsive kind heart of a vampire lured by him into this whirlwind. It is plain old entertainment watching this dynamic from time to time; Vanitas’s teasing, and exasperated reactions by Noé are just side-splitting enough to make everyone giggle about them. But behind the joke, there is a profound, unspoken trust. Noé looks beyond the bravado that surrounds Vanitas, and even Vanitas looks to Noé for more support than he likes to admit. Their friendship combines sarcasm with emotional vulnerability, mixed with the most unexpected moments of tenderness. If you love duos that are hilarious, mysterious, and emotionally entwined, this pair will hook you.
42. Sherlock Holmes & William Moriarty
- Anime: Moriarty the Patriot
- IMDb Rating: 8.0/10
- Streaming Platform: HiAnime, Netflix, Jio Cinema
A detective and a mastermind locked in a battle of wits—Sherlock Holmes and William Moriarty’s dynamic in Moriarty the Patriot is nothing short of electric. On the surface, they should be enemies: one upholding justice through the law, the other manipulating society to bring about his own brand of justice. Yet, beneath their rivalry, there’s an unspoken respect and fascination between them.
Every scene between the two is drenched with the electricity of a confrontation, high intelligence, and exhilarating plays on the psyche. It isn’t about each one outdoing the other: instead, they know each other more than others, in this chillingly intriguing world. Love seeing couples go toe-to-toe, respectful but also combative, covered with mystery, and suspense- well, I will be thoroughly glued to these games of cat-and-mouse.
41. Best Anime Duos of All Time: Eren & Zeke
- Anime: Attack on Titan: The Final Season
- IMDb Rating: 9.1/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll
A bond forged in ideology, betrayal, and the weight of history—Eren and Zeke’s relationship is as thrilling as it is tragic. What once symbolized defiance and freedom now stands as opposites, both sides engaged in a grotesque plan of salvation.
The uneasy alliance of Eren and Zeke is filled with tension, manipulation, and mind games, making every conversation a battle of wits. Yet, beneath it all lies a deceptive façade of brotherhood, but these moments make their relationship anything but forgettable. Their relationship makes you constantly question who is who and what they are doing, making their story so thrillingly painful. If you enjoy duos with mixed philosophy, betrayal, and psychological warfare, then this journey will leave you speechless in Attack on Titan: The Final Season.
40. Senku & Chrome
- Anime: Dr. Stone
- IMDb Rating: 8.1/10
- Streaming Platform: HiAnime, Crunchyroll, Netflix
Brains meet endless curiosity in the most dynamic duo of Dr. Stone, Senku, and Chrome. Senku, the genius scientist with an encyclopedic mind, and Chrome, the self-taught sorcerer-turned-inventor, make science feel like an adventure. Their friendship is a perfect mix of comedy and inspiration—Senku’s smug brilliance meets Chrome’s unrelenting excitement, creating some of the most entertaining moments in the series.
But it’s not just about laughs; they push each other to new heights, proving that intelligence and passion can change the world. Their partnership transforms ordinary objects into mythological revelations as if every victory is earned. For those who love seeing the comedic, artistic combination lead to the unrelenting desire to understand, fans will not forget the relationship between the protagonists of Dr. Stone
39. Aqua & Ruby Hoshino
- Anime: Oshi no Ko
- IMDb Rating: 8.3/10
- Streaming Platform: HiAnime, Netflix, Prime Video
Tied by tragedy, an acting sibling duo seeking fame—is the bond between Aqua and Ruby in Oshi no Ko, as heart-wrenching as it sounds. Aqua, filled with revenge, conceals his pain behind a cold, calculating exterior, and Ruby, full of dreams and determination, brings light to their dark reality. Their interactions are a mix of bittersweet humor and deep emotional moments showing how two people can deal with the same past in vastly different ways. Aqua acts as a protector for Ruby, and Ruby is a reminder of the innocence and love they lost.
Their journey in the entertainment world is full of mystery, broken hearts, and the unbreakable bond between siblings. So, if you enjoy duos that balance between darkness and hope, their story is a must-watch.
38. Takemichi & Chifuyu
- Anime: Tokyo Revengers
- IMDb Rating: 7.8/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll
Takemichi and Chifuyu’s partnership in Tokyo Revengers is all about brotherhood, loyalty, and pure ride-or-die energy. The duo is one of the most heartfelt friendships in anime. Takemichi is the underdog time-traveler, but Chifuyu is the unwavering support system that keeps him going. Their dynamic is both hilarious and deeply emotional—Chifuyu believes in Takemichi when no one else does, and Takemichi, despite his struggles, never gives up. From ridiculous plans to brutal gang battles, their friendship remains unshakable, making every moment between them feel earned. If you are a fan of duos consisting of trust, persistence, and fraternal love, this will have you crying and laughing with them, and cheering them throughout.
37. Best Anime Duos of All Time: Daisuke Kambe & Haru Kato
- Anime: The Millionaire Detective – Balance: Unlimited
- IMDb Rating: 7.2/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll, Prime Video
Unlimited money with a detective to solve problems on the nth level and a cop who holds justice in their heart, no wonder Daisuke Kambe and Haru Kato make up a comedic duo. The arrogant, cool billionaire Daisuke and the hotheaded officer Haru, who is the first man to really care about proper police work, form a battle. Their constant argument over ethics, money, and methods provides much of the show’s comedic gold.
Beyond this, their partnership slowly builds mutual respect: Daisuke for being more than just a playboy with deep pockets, and Haru in understanding that the value of real justice has finally been given meaning. The Millionaire Detective – Balance: Unlimited fan knows the witty banter, stylish action, and unexpected emotional depth, these two hold that will keep you entertained from start to finish.
36. Frieren & Fern
- Anime: Frieren: Beyond Journey’s End
- IMDb Rating: 8.9/10
- Streaming Platform: HiAnime, Crunchyroll, Netflix
A quiet yet deeply moving duo, Frieren, and Fern in Frieren: Beyond Journey’s End explore the meaning of time, connection, and growth. Frieren is an immortal elf who used to consider humans transient, but things change with the help of Fern, her determined apprentice. This relationship is rather subtle yet powerfully effective for both of them: Fern takes on the roles of a pupil and a counterbalance to the life of Frieren; Frieren, through these quiet observations, teaches Fern both magic and life.
Their bond is not based on grand gestures but on small, meaningful moments that show how much they have come to rely on each other. If you love duos that feel gentle yet profound, with emotional storytelling that lingers long after the episode ends, these two will touch your heart.
35. Yumeko Jabami & Ryota Suzui
- Anime: Kakegurui
- IMDb Rating: 7.1/10
- Streaming Platform: HiAnime, Netflix
A wild ride, a fearless gambler and her demurring voice of reason Jabami Yumeko and Suzui Ryota, from Kakegurui. Yumeko, a gambling addict who thrives on risk, and Ryota, with a bit of sanity in a room of morons, barely keeping up with her madness. Their interactions are pure comedy- Yumeko dragging him into insane bets while he desperately tries not to let either of them slip into disaster.
But despite all the mayhem, their connection is somehow cute; Ryota cannot comprehend Yumeko’s fascination, but he remains faithful and supportive to her at critical times. If you enjoy the combo of intense action with some comical elements and unspoken trust, then you will love these two characters as well.
34. Ron Kamonohashi & Totomaru Isshiki
- Anime: Ron Kamonohashi: Deranged Detective
- IMDb Rating: 7.1/10
- Streaming Platform: HiAnime, Crunchyroll, Netflix
A genius detective with a troubled past and an earnest cop who merely wants to get his job done: Ron Kamonohashi and Totomaru Isshiki are together in a riot in Ron Kamonohashi: Deranged Detective. Eccentric yet brilliant in the detective part, Ron seems to always be ten steps ahead. The kind and gentle-hearted, clueless Officer Totomaru struggles to even catch up.
Their banter is a comic cocktail of smarmy Ron’s tricks and frustrated Totomaru, yet, together they surprise. Beyond comedy lies the deep emotional base; Totomaru believes in Ron when nobody else does, and Ron finally has a reason to keep on solving mysteries after the checkered past. So if you love mystery-solving pairs infused with wittiness, wrapped in a tight, emotional center, that nobody would possibly like, it would be pretty much impossible not to fall under the spell.
33. Best Anime Duos of All Time: Isagi Yoichi & Bachira Meguru
- Anime: Blue Lock
- IMDb Rating: 8.2/10
- Streaming Platform: HiAnime, Netflix, Crunchyroll
Yoichi and Bachira Meguru of Blue Lock is a pack of strikers looking for their ego and a free-spirited playmaker who feeds off chaos as thrilling as it is emotional. On the field, Isagi, the analytical and deliberate forward, finds himself initially drawn towards Bachira’s explosive energy that wracks the very foundations of football with a style that’s unpredictable.
Their chemistry is undeniable—Bachira’s fearlessness opens up untapped possibilities in Isagi, and Isagi’s strategic nature helps Bachira ground his wild instincts. But for them, their bond is not strictly about teamwork but about pushing each other towards new heights when it allows this dynamic to push them to be foes. Their moments are a summation of electricity, deep trust, and mutual admiration. If you like duos that are exciting, and emotional, and bring jaw-dropping soccer plays, these two will keep you on the edge of your seat.
32. Kazuki Kurusu & Rei Suwa
- Anime: Buddy Daddies
- IMDb Rating: 7.9/10
- Streaming Platform: HiAnime, Crunchyroll
Two assassins turned accidental fathers—Kazuki Kurusu and Rei Suwa’s dynamic in Buddy Daddies is equal parts action, comedy, and heartwarming chaos. Kazuki, the loud and outgoing planner, clashes with Rei, the quiet and deadly sharpshooter, but their differences make them the perfect team. When they unexpectedly take in a young girl Miri. their lives turn upside down, leading to hilarious parenting mishaps and surprisingly tender moments.
Kazuki’s endless energy balances Rei’s stoic nature, but beneath their banter, there’s a deep sense of family forming between them. Watching them navigate deadly missions while learning to be dads is both hilarious and emotional. This dynamic duo will sweep you off your feet if you enjoy action-packed, found-family stories with humor and heartfelt moments.
31. Worick Arcangelo & Nicolas Brown
- Anime: Gangsta
- IMDb Rating: 7.2/10
- Streaming Platform: HiAnime, Crunchyroll
Blood, loyalty, and survival is what molds the unbreakable bond between Worick Arcangelo and Nicolas Brown as they go through the gruesome realities of Gangsta. The charismatic ladies’ man, Worick, strikes an excellent balance between the deadly silence of Nicolas, the enforcer who is a deaf mercenary.
Their chemistry is undeniable—Worick translates for Nic, who is deaf, while Nic protects Worick with unwavering loyalty. Shared past filled with pain, and their trust for each other is absolute. When they take down ruthless gangs or share a cigarette, their connection feels real and unbreakable. Their dynamic is raw, emotional, and effortlessly cool. If you love duos with a mix of action, dark pasts, and a rare kind of friendship that transcends words, these two are impossible to forget.
30. Best Anime Duos of All Time: Luffy and Zoro
- Anime: One Piece
- IMDb Rating: 8.9/10
- Streaming Platform: Crunchyroll
One Piece is an anime that has held out his fanbase for the last 2 decades. It is about finding the greatest treasure left by the early pirates. Now the new generation of pirates is on a voyage to find the hidden treasure.
Luffy and Zoro are one of the best duos in the Anime world. Their bonding and mentality make a perfect pair. Goofy Luffy and Serious Zoro handle the crew like butter.
29. Itadori Yuji and Aoi Todo
- Anime: Jujutsu Kaisen
- IMDb Rating: 9.3/10
- Streaming Platform: Crunchyroll
Jujutsu Kaisen is an anime with a rapidly growing fan base. All are crazy about the battle between the sorcerer and the curses. They have crazy powers and abilities which make Jujutsu kaisen a impressive and interesting anime.
Itadori is the main character in Jujutsu Kaisen and Todo is a senior to Itadori in the Academy. They meet during the inter-academy battle and both develop a unique brotherhood. Their unique fighting style combined makes a brutal fight look beautiful.
28. Magna Swing and Luck Voltia
- Anime: Black Clover
- IMDb Rating:9.5/10
- Streaming Platform: Crunchyroll
Black Clover is considered one of the best new-gen anime. The story is about a boy called Asta who aspires to become the wizard king. But he has no magical power.
Magna Swing and Luck Voltia are senior members of the squad named Black Bulls where Asta joined. Magna’s fire ability and Luck’s lighting magic powers make them a deadly pair. Their personalities always clash as Luck never stops making fun of Magna.
27. Best Anime Duos of All Time: Hyakkimaru and Dororo
- Anime: Dororo
- IMDb Rating: 8.3/10
- Streaming Platform: Crunchyroll
Dororo is a short anime based on a person named Hyakkimaru whose goal is to retrieve his body from the demons who took his body parts during his birth. In this journey, he is accompanied by a companion named Dororo.
In the beginning, Hyakkimaru was unable to talk or express any emotions due to his lack of body parts. As time passed and he obtained his body parts one by one Dororo helped him to adapt to them and make Hyakkimaru an understanding person.
26. Osamu Dazai and Chūya Nakahara :
- Anime: Bungo Stray Dogs
- IMDb Rating: 7.8/10
- Streaming Platform: Crunchyroll
Bungo Stray Dogs is an anime based on wars between a detective agency, a mafia gang nd other groups who also possess some powerful abilities. The war is for dominance over the city.
Osamu Dazai is a former member of the mafia gang and used to work with Chūya Nakahara. Dazai’s reckless and childish behaviour combined with Chuya’s duty sense and irritation towards Dazai makes them a great pair. Their powers combined can cross limits.
25. Naruto and Sasuke
- Anime: Naruto
- IMDb Rating: 8.3/10
- Streaming Platform: Netflix
Naruto is a popular shōnen series that primarily concentrates on the friendship between Naruto and Sasuke. The unique bond shared by the two very different yet similar individuals catches the audience’s attention apart from a unique storyline.
Everyone gave up on Sasuke when he abandoned his village to earn power, except for Naruto. Naruto taught him the true meaning of friendship and made him realize that there is more to life if he thinks optimistically.
24. Best Anime Duos of All Time: Kirito and Asuna
- Anime: Sword Art Online
- IMDb Rating: 7.5/10
- Streaming Platform: Netflix
Sword Art Online is an anime that screens a power couple whose approaches towards the tasks in games blend. In the early stage, the roots of anime were mainly based on their fantastic sword skills and techniques. If the anime fans dig deeper, they will find out that their methods complement each other.
Kirito and Asuna work as a perfect team as Kirito understands the game more vividly, and Asuna is determined to finish it.
23. Joseph And Caesar
- Anime: Jojo’s Bizarre Adventure
- IMDb Rating: 8.5/10
- Streaming Platform: Netflix
The show JoJo’s Bizarre Adventure certainly pulled out one of the significant iconic duos, but none of them matches the friendship of Joseph Joestar and Caesar Zeppeli. Sadly, the first meeting couldn’t form a foundation for their friendship as they ended up having a small fight.
As the show progressed, the two became close friends. Caesar even forfeited his own life to get the antidote for Joseph, representing the depth of their friendship.
22. Ash And Pikachu
- Anime: Pokemon
- IMDb Rating: 7.5/10
- Streaming Platform: Netflix
In almost every streetinf the world, the adorable characters of Pikachu and Ash are known. Like the duo, Tom and Jerry have an unbreakable friendship, and this series discovers new pages of adventure in every episode.
21. Best Anime Duos of All Time: Twelve and Nine
- Anime: Terror in Resonance
- IMDb Rating: 7.9/10
- Streaming Platform: Netflix
The powerful couple from the anime show Terror in Resonance drop bombs at buildings and challenge the world as they have perfect compatibility. Both of them are extremely smart and rebellious. Their genuine friendship leaves the viewers in awe every single time.
20. Izuku Midoriya and Katsuki Bakugo
- Anime: My Hero Academia
- IMDb Rating: 8.4/10
- Streaming Platform: Netflix
Izuku Midoriya and Katsuki Bakugo from My Hero Academia share the most epic rivalries anime fans have ever witnessed. They have a weird relationship as they are mortal enemies, but they appreciate each other’s skills deep down. Their rivalry pushes them to do their best. This strange bond forces them to get better unknowingly.
19. Kamina and Simon
- Anime: Tengen Toppa Gurren Lagann
- IMDb Rating: 8.3/10
- Streaming Platform: Netflix
The iconic characters of Kamina and Simon are one of the best anime duos from Tengen Toppa Gurren Lagann. Their friendship has inspired a lot of anime heads. They push each other’s boundaries and motivate them to be more independent with abilities. Their powers complement each other during battle.
18. Kakashi and Mighty Guy
- Anime: Naruto
- IMDb Rating: 8.3
- Streaming Platform: Netflix
Kakashi and Mighty Guy are the most rebellious twosome that serves every time they are together. Fans gush over their bro code which is seen in different aspects of the anime.
17. Best Anime Duos of All Time: Gintoki And Katsura
- Anime: Gintama
- IMDb Rating: 8.7/10
- Streaming Platform: Crunchyroll
Gintama is an anime that portrays a duo with solid personalities, Gintoki and Katsura. Throughouth the show, the two have shown commendation for each other. Even though they walk on different life paths, they are still trained by the same teacher. The teaching was the result of them saving each other in different situations.
16. Meliodas And Ban
- Anime: Seven Deadly Sins
- IMDb Rating: 7.9/10
- Streaming Platform: Netflix
The series Seven Deadly Sins has produced some of the most extraordinary partnerships, but none of them can outshine the companionship shared by Meliodas And Ban. That’s the most genuine kind of friendship.
Despite the conflict between various races, the heir to the Demon throne and an immortal human still managed to form one of the purest forms of friendship with each other. Their friendship proves to be a ray of hope in their dark and violent world. Indeed they are one of the best anime duos we have ever come across.
15. Kagome & Inuyasha
The character of Kagome and Inuyasha feels like they are made for each other. What’s impressive is how well they go with each other. Whether it’s Kagome’s clingy personality or Inuyasha’s grumpiness, we have umpteen reasons to watch this incredible series.
14. Best Anime Duos of All Time: Sailor Moon & Sailor Venus
- Anime: Sailor Moon
- IMDb Rating: 7.6/10
- Streaming Platform: Netflix
We guarantee you that this twin-sister duo is the most adorable anime duo in the world of anime. They are unbelievably identical to each other. Not only this, they share an undying love for each other. Sailor Venus is ready to sacrifice her life for Sailor Moon. They protect each other on the battlefield, making them the most dynamic duo ever.
We can’t get over the fact that since their fighting styles are unique, they prove to be an excellent match in front of their competitors. Their cover for each other in the fight is undoubtedly the most exciting sequence.
13. Hunk & Pidge
- Anime: Voltron
- IMDb Rating: 8/10
- Streaming Platform: Netflix
As evident, Hunk & Pidge are the best of friends. Their chemistry makes it impossible not to think of them as a single entity. Pidge is extremely intelligent and knows pretty much about everything, Hunk is forever hungry, and his favorite hobby is binge-eating.
The bond between both friends acts as fantastic comedic fodder. The weird antics often get them into trouble, and Pidge has to find solutions. They always have each other’s back when things go south.
12. Maka & Soul
- Anime: Soul Eater
- IMDb Rating: 7.8/10
- Streaming Platform: Hulu
You might find it hard to see why this opposite duo from the Soul Eater series is brought together. Although one is a non-powered girl the other can transform into a mighty scythe. But there is some spark that binds them together.
What makes them unique is that they don’t have a mainstream romantic tension between them. Their main goal is to combat the evil forces. They understand each other’s abilities, and they work accordingly.
11. Kageyama & Hinata
- Anime: Haikyuu!!
- IMDb Rating: 8.7/10
- Streaming Platform: Crunchyroll
It was evident that Kageyama & Hinata are a power duo from the beginning of the series. These two have very distinct personalities except for two things; their love for playing volleyball and insane stubbornness. They can’t be categorized as friends, they are more of teammates, and we adore their unique bond.
10. Best Anime Duos of All Time: Gon & Killua
- Anime: Hunter X Hunter
- IMDb Rating: 9/10
- Streaming Platform: Netflix
The fantastic pair of Gon & Killua is sure to leave you amazed as they share of a one-of-a-kind friendship. Killua from Hunter X is brought up to be an assassin and was destined for a lifetime of solitude, detached from the world. His unexpected meeting with kind-hearted Gon, who has a bubbly personality, changed his life forever.
The makers of Hunter X Hunter did an excellent job in weaving a sweet tale about them. And, we still haven’t recovered from their beautiful friendship, right folks?
9. Sekkekkyu & Hakkekkyu
- Anime: Cells At Work
- IMDb Rating: 7.5/10
- Streaming Platform: Netflix
It’s a fact that red blood cells can’t function without white blood cells fighting for them. The show Cells At Work presented a more excellent bond between Erythrocyte (Sekkekkyū) and Neutrophil (Hakkekkyū) that is seriously unbeatable. It’s interesting to find out that their pairing happened long before they even met, and they already established a powerful link between them.
They both work as a great team, and two seasons are painfully not enough to experience an incredible partnership between them. We need more of it!
8. Light & L
- Anime: Death Note
- IMDb Rating: 9/10
- Streaming Platform: Netflix
Light & L are one of the most iconic pairs in the anime community. The legendary anime Death Note features a strange relationship between Light and L. They both have been fighting for similar reasons, but their goals are opposite each other. The makers did a fantastic job keeping them together as they are more than just perfect for each other.
The Death Note duo might be facing a little controversy, but that doesn’t stop us from including them in our list of the most popular anime duos.
Read More: The Best Anime Like Death Note To Watch Right Now
7. Best Anime Duos of All Time: Isaac & Miria
- Anime: Baccano!
- IMDb Rating: 8.3/10
- Streaming Platform: Amazon Prime Video
The unique relationship of Isaac & Miria makes the show Baccano! Hilarious. They are certainly the best partners in crime, and we love how they bring out the much-needed humor and fun, despite having a pretty dark background. They are certainly not the most intelligent group as they lack some common sense, but they have serious friendship goals.
6. Mustang & Hawkeye
- Anime: Fullmetal Alchemist
- IMDb Rating: 9.1/10
- Streaming Platform: Netflix
Interestingly, this anime duo is that they both are not good at expressing their feelings, and they appear to be a mismatch at first glance, but you need to go through the entire series to find out why they are perfect for each other.
The two characters have unique personalities, but they share a list of similar traits simultaneously. They both seem to share a bold personality as they are fiery, strong and brave. They seem to complete each other exquisitely, and we go gaga every time they appear on screen caring for each other.
Mustang & Hawkeye have the most unstoppable bond as the kind of trust shared by both isn’t seen in most couples nowadays. They continuously push each other to get better without forgetting about their messed-up past, bringing them closer. Our heart beats for this power couple!
5. Edward & Alphonse
- Anime: Fullmetal Alchemist
- IMDb Rating: 9.1/10
- Streaming Platform: Netflix
Edward Elric is the main protagonist of the Fullmetal Alchemist anime series. Edward’s relationship with his younger brother Alphonse is easily the strongest. Although Edward and Alphonse’s relationship is featured as siblings, they can be easily identified as best friends. Edward is highly protective about his brother, and he is seen caring for him in a parental way, and we can’t get enough of this sweet little bond.
The two characters went through many adventures and hardships together, and we have seen their bond maturing as the series progressed. Their unique connection has now developed into an unbreakable bond, and we would like to keep them in the category of one of the best anime duos in the anime industry.
4. Best Anime Duos of All Time: Sora & Shiro
- Anime: No Game No Life
- IMDb Rating: 7.7/10
- Streaming Platform: Crunchyroll
The anime series No Game No Life revolves around two sibling duo, Sora & Shiro, who do nothing all day except play games. The intense emotional bond shared by the two characters has been portrayed perfectly, and you will instantly feel attached to them.
The two characters are among the most iconic anime duos, and we adore them for their excellent partnership. Their ability to break down every move and strategically plan for the next one will leave you awestruck at times. Their strong connection makes them achieve victory at every battle. Although they are opposite to each other, their love for video games unites them to form a strong bond.
3. Goku & Vegeta
- Anime: Dragon Ball
- IMDb Rating: 8.5/10
- Streaming Platform: Hulu
We all have obsessed over the love-hate relationship between Son Goku and Vegeta at some point in our lives. They share complicated histories filled with many betrayals, murder attempts, and kidnapping, but what’s constant is their unbreakable bond, which makes them get through all the tough times.
This sweet-sour relationship portrayed in Dragon Ball undoubtedly tops our list of having the most peculiar relationship we have ever experienced.
What’s hilariously ironic is the fact that their two sons, Trunks and Gotten, are best friends. The rivalry between the two characters drives them to work extra hard to outshine the other, making them the most potent duo ever.
2. Natsu & Happy
- Anime: Fairy Tail
- IMDb Rating: 8/10
- Streaming Platform: Netflix
As much as the two adorable characters, Natsu & Happy, share the sweetest friendship in the series, we can’t get enough of their unbreakable bond. Natsu Dragneel is a mage of the Fairy Tail Guild and a member of Team Natsu. He is also among the five Dragon Slayers sent to the future from four hundred years past with the primary motive of defeating Acnologia.
Happy is also a member of Fairy Tail Guild and Team Natsu. Despite his small stature and strange appearance, he possesses vast knowledge about the magic world and is highly loyal to his teammates and fellow guild members, especially Natsu.
The anime features the close friendship shared by the two characters as Happy seems to mirror quite a few of Natsu’s Characteristics. Happy even prevented Natsu from killing his brother Zeref, and you know it’s a heart-to-heart relationship when one is the reason for the other person’s character development.
1. Best Anime Duos of All Time: Saitama & Genos
- Anime: One Punch Man
- IMDb Rating: 8.7/10
- Streaming Platform: Netflix
One Punch Man is about an invincible superhero named Saitama who can defeat anyone in just one punch. The story revolves around Saitama’s journey to become an admirable hero in people’s eyes.
Although the main character, Saitama, in this anime series doesn’t need the help of anybody to break the bones of the villains, his one punch is considerably enough to shatter the evil motives, and he still appreciates the company of other superheroes and Genos tops his list.
Genos is Saitama’s disciple. No one understands how extreme it is to defeat the dangerous villains with one punch, except for Genos. While other heroes make fun of Saitama’s abilities, Genos remains amazed by his mentor’s powers and makes sure One Punch Man is aware of it.
Their bond is undoubtedly an inspiration for today’s modern world, full of people who envy each other’s strength and don’t want anyone to outshine them.
Read More: The Best Anime Like One Punch Man To Watch Right Now
